Origin and Properties of Bakuchiol

Bakuchiol gets its name from the plant "Bakuchiol" (Psoralea corylifolia), native to India and traditionally used in Ayurvedic and Chinese medicine for centuries. It is a plant rich in antioxidants, known for its anti-inflammatory properties and benefits for the skin [1]. Bakuchiol stands out for its ability to mimic the effects of retinol without the potentially irritating side effects associated with it [2].

Retinol, a form of vitamin A, is widely recognized for its effectiveness in treating wrinkles, fine lines, and hyperpigmentation [3]. However, it can cause increased skin sensitivity, peeling, and redness in some individuals [4]. Bakuchiol, often named the "natural alternative to retinol," offers a gentle and well-tolerated alternative, without the undesirable effects often seen with retinol [2].

Benefits of Bakuchiol for the Skin

Bakuchiol stimulates collagen production, contributing to improved skin firmness and elasticity. It also helps to reduce the appearance of wrinkles and fine lines, leaving the skin smoother and younger-looking. Simultaneously, by gently exfoliating the skin, bakuchiol promotes cell renewal and contributes to a more even texture and improved skin tone. One of the most appreciated characteristics of bakuchiol is its gentleness. Individuals with sensitive skin that may not always tolerate retinol can benefit from the soothing properties of bakuchiol [5].

Bakuchiol represents an exciting development in the field of skincare, providing a natural and gentle alternative to retinol. With its anti-aging, exfoliating, and antioxidant properties, it can contribute to brighter and younger-looking skin without the potential drawbacks associated with other more aggressive ingredients. Bakuchiol is one of the active ingredients in the CLEAR SKIN SUPERCHARCHED SERUM.

Référence

[1] Bluemke A, Ring AP, Immeyer J, Hoff A, Eisenberg T, Gerwat W, Meyer F, Breitkreutz S, Klinger LM, Brandner JM, Sandig G, Seifert M, Segger D, Rippke F, Schweiger D. Multidirectional activity of bakuchiol against cellular mechanisms of facial ageing - Experimental evidence for a holistic treatment approach. Int J Cosmet Sci. 2022 Jun;44(3):377-393. doi: 10.1111/ics.12784. Epub 2022 Jun 9. PMID: 35514037; PMCID: PMC9328396.
[2] Dhaliwal S, Rybak I, Ellis SR, Notay M, Trivedi M, Burney W, Vaughn AR, Nguyen M, Reiter P, Bosanac S, Yan H, Foolad N, Sivamani RK. Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. Br J Dermatol. 2019 Feb;180(2):289-296. doi: 10.1111/bjd.16918. Epub 2018 S
[3] Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-48. doi: 10.2147/ciia.2006.1.4.327. PMID: 18046911; PMCID: PMC2699641.
[4] Fluhr JW, Vienne MP, Lauze C, Dupuy P, Gehring W, Gloor M. Tolerance profile of retinol, ret
[5] Draelos ZD, Gunt H, Zeichner J, Levy S. Clinical Evaluation of a Nature-Based Bakuchiol Anti-Aging Moisturizer for Sensitive Skin. J Drugs Dermatol. 2020 Dec 1;19(12):1181-1183. doi: 10.36849/JDD.2020.5522. PMID: 33346506.
[6] Adhikari S, Joshi R, Patro BS, Ghanty TK, Chintalwar GJ, Sharma A, Chattopadhyay S, Mukherjee T. Antioxidant activity of bakuchiol: experimental evidences and theoretical treatments on the possible involvement of the terpenoid chain. Chem Res Toxicol. 2003 Sep;16(9):1062-9. doi: 10.1021/tx034082r. PMID: 12971793.

Julie-mobhat

Par Julie Mohbat

Master 2 in Life Sciences Engineering, EPFL, Lausanne, Switzerland

Julie is a Master 2 graduate in Life Sciences Engineering at EPFL, specialising in neuroscience and neuroengineering after a Bachelor degree at the same school. Her skills lie at the interface between engineering, life sciences, biochemistry and cellular and molecular biology with a focus on biotechnological innovations for medicine.

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